Article
Multiple testing for SNP-SNP interactions.
Statistical applications in genetics and molecular biology - 1 Jan 2007
Boulesteix Anne-Laure, Strobl Carolin, Weidinger Stefan, Wichmann H-Erich, Wagenpfeil Stefan
Abstract excerpt
Most genetic diseases are complex, i.e. associated to combinations of SNPs rather than individual SNPs. In the last few years, this topic has often been addressed in terms of SNP-SNP interaction patterns given as expressions linked by logical operators. Methods for multiple testing in high-dimensional settings can be applied when many SNPs are considered simultaneously. However, another less well-known multiple...
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