Article
Restoration of ovulation after unilateral ovariectomy in a woman with McCune-Albright syndrome: a case report.
European journal of endocrinology - 1 Jan 2008
Lavoué Vincent, Morcel Karine, Bouchard Philippe, Sultan Charles, Massart Catherine, Grall Jean-Yves, Lumbroso Serge, Laurent Marie-Christine
Abstract excerpt
INTRODUCTION: McCune-Albright syndrome (MAS) is characterized by peripheral precocious puberty, café-au-lait spots, and polyostotic fibrous dysplasia. This syndrome is due to a post-zygotic mutation of the GNAS1 gene with mosaic distribution and unilateral predominance. Clinical manifestations depend on the tissues carrying the mutation. We describe the ovarian function before and after unilateral ovariectomy in...
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