Article
Hyperthyroidism in McCune-Albright syndrome with a review of thyroid abnormalities sixty years after the first report.
Thyroid : official journal of the American Thyroid Association - 1 Jun 1997
Mastorakos G, Mitsiades N S, Doufas A G, Koutras D A
Abstract excerpt
We present a patient with hyperthyroidism associated with McCune-Albright syndrome (MAS). MAS is a sporadic genetic disease characterized by polyostotic fibrous dysplasia, cafe au lait cutaneous spots and endocrinopathies (peripheral precocious puberty, thyroidopathies, acromegaly, etc.). It is caused by an activating mutation of the gene for the Gs alpha membrane-associated protein, which mediates the...
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