Article
Highly variable penicillin resistance determinants PBP 2x, PBP 2b, and PBP 1a in isolates of two Streptococcus pneumoniae clonal groups, Poland 23F-16 and Poland 6B-20.
Antimicrobial agents and chemotherapy - 1 Mar 2008
Izdebski Radoslaw, Rutschmann Jens, Fiett Janusz, Sadowy Ewa, Gniadkowski Marek, Hryniewicz Waleria, Hakenbeck Regine
Abstract excerpt
Penicillin-binding proteins (PBPs) in representatives of two Streptococcus pneumoniae clonal groups that are prevalent in Poland, Poland 23F-16 and Poland 6B-20, were investigated by PBP profile analysis, antibody reactivity pattern analysis, and DNA sequence analysis of the transpeptidase (TP) domain-encoding regions of the pbp2x, pbp2b, and pbp1a genes. The isolates differed in their MICs of beta-lactam...
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