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Article

Role of the alfalfa mosaic virus methyltransferase-like domain in negative-strand RNA synthesis.

Journal of virology - 1 Nov 2002

Vlot A Corina, Menard Aymeric, Bol John F

Abstract excerpt

RNAs 1 and 2 of the tripartite genome of alfalfa mosaic virus (AMV) encode the replicase proteins P1 and P2, respectively. P1 contains a methyltransferase-like domain in its N-terminal half, which has a putative role in capping the viral RNAs. Six residues in this domain that are highly conserved in the methyltransferase domains of alphavirus-like viruses were mutated individually in AMV P1. None of the mutants...

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Identifiers

PMID: 12388692
DOI: 10.1128/jvi.76.22.11321-11328.2002
PMCID: PMC136773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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