Article
Enantiospecific gas chromatographic-mass spectrometric analysis of urinary methylphenidate: implications for phenotyping.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 1 Feb 2008
LeVasseur Natalie L, Zhu Hao-Jie, Markowitz John S, DeVane C Lindsay, Patrick Kennerly S
Abstract excerpt
A chiral derivatization gas chromatographic-mass spectrometric (GC-MS) method for urine methylphenidate (MPH) analysis was developed and validated to investigate preliminary findings regarding a novel MPH poor metabolizer (PM). Detection was by electron impact (EI) ionization-selected ion monitor...
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