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Article

Disrupted OmpC causes osmosis sensitivity of Escherichia coli in alkaline medium.

Journal of genetics and genomics = Yi chuan xue bao - 1 Dec 2007

Wang Yuqi, Wang Lingling, Sun Yirong, Chen Yicai, Zhu Lei, Guo Lixia, Luo Biao, Wang Haihong

Abstract excerpt

The Escherichia coli strain DH42 is sensitive to high osmolarity in an alkaline medium. Using mini-Tn5 mutagenesis, construction of mutant strains by homologous recombination and subcloning of DNA fragment techniques, gene ompC was identified as the key factor that, once disrupted, caused osmosis-sensitivity of E. coli strain DH42 grown in an alkaline medium. Through P1 transduction, a mutant strain, D9 (W3110...

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PMID: 18155626
DOI: 10.1016/S1673-8527(07)60129-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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