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Article

Jekyll & Hyde: evolution of a superfamily.

Chemistry & biology - 1 Dec 2007

Martinis Susan A, Joy Pang Yan Ling

Abstract excerpt

Aminoacyl-tRNA synthetase mutations have been linked to neurological diseases, but aminoacylation may be unaffected. This protein superfamily also performs many other diverse functions. Yang et al. insightfully engineer a single mutation to unmask a cell signaling activity of tyrosyl-tRNA synthet...

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Source

Identifiers

PMID: 18096496
DOI: 10.1016/j.chembiol.2007.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18096496-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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