Article
Primary and secondary infections of Macaca fascicularis monkeys with Asian and American genotypes of dengue virus 2.
Clinical and vaccine immunology : CVI - 1 Mar 2008
Bernardo Lidice, Izquierdo Alienys, Prado Irina, Rosario Delfina, Alvarez Mayling, Santana Emidalys, Castro Jorge, Martínez Rafael, Rodríguez Rosmari, Morier Luis, Guillén Gerardo, Guzmán María G
Abstract excerpt
The goal of this study was to compare the immune response and the protection capacity induced by the dengue virus 2 (DENV-2) American and Asian genotypes in Macaca fascicularis monkeys. Animals were infected with American or Asian DENV-2 strains and challenged 1 year later with a DENV-2 Asian genotype strain. The viremia and monkey antibody levels were similar for the different strains after primary and secondary...
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