Article
Lessons that can be learned from patients with diabetogenic mutations in mitochondrial DNA: implications for common type 2 diabetes.
Current opinion in clinical nutrition and metabolic care - 1 Nov 2007
Maassen Johannes A, 't Hart Leen M, Ouwens D Margriet
Abstract excerpt
PURPOSE OF REVIEW: To discuss the role of mitochondria in the development of type 2 diabetes. RECENT FINDINGS: Some mutations in mitochondrial DNA are diabetogenic due to a gradual decline in insulin secretion by the pancreas. These mutations also result in abnormalities in lipid metabolism. A si...
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