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Article

The Phototoxicity of Aged Human Retinal Melanosomes<sup>†</sup>

17 Dec 2007

Abstract excerpt

The purpose of this study was to determine whether an age-related increase in photoreactivity of human retinal melanosomes (MS) can cause phototoxicity to retinal pigment epithelium (RPE) cells. MS were isolated post mortem from young (20-30 years, young human melanosomes [YHMs]) and old (60-90 years, old human melanosomes [OHMs]) human eyes and from young bovine eyes (bovine melanosomes [BMs]). Confluent...

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PMID: 18086241
DOI: 10.1111/j.1751-1097.2007.00259.x

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