Article
Pharmacogenetic study of atypical antipsychotic drug response: involvement of the norepinephrine transporter gene.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2008
Méary A, Brousse G, Jamain S, Schmitt A, Szöke A, Schürhoff F, Gavaudan G, Lancon C, Macquin-Mavier I, Leboyer M, Llorca P M
Abstract excerpt
The identification of genetic factors underlying individual differences in antipsychotic drug response is of major interest. We investigated the involvement of two norepinephrine transporter gene polymorphisms in response to antipsychotics, comparing patients with strong and weak response to olanzapine and risperidone. We prospectively assessed short-term drug response in 75 Caucasian schizophrenic patients...
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