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Article

Differential binding of mutant (R116C) and wildtype alphaA crystallin to actin.

Current eye research - 1 Dec 2007

Brown Zachery, Ponce Aldo, Lampi Kirsten, Hancock Lynn, Takemoto Larry

Abstract excerpt

PURPOSE: Quantitate the interaction of mutant (R116C) and wildtype human alphaA crystallins with actin. METHODS: AlphaA crystallins, expressed in a recombinant system, were purified, followed by passage through an actin affinity column. RESULTS: Binding of mutant alphaA crystallin was significantly less than binding of wildtype alphaA crystallin. CONCLUSIONS: The R116C mutation of alphaA crystallin found in human...

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Identifiers

PMID: 18085469
DOI: 10.1080/02713680701769989
PMCID: PMC2425674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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