Article
Antimalarial resistance and DHFR/DHPS genotypes of Plasmodium falciparum three years after introduction of sulfadoxine-pyrimethamine and amodiaquine in rural Tanzania.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Feb 2008
Eriksen J, Mwankusye S, Mduma S, Veiga M I, Kitua A, Tomson G, Petzold M G, Swedberg G, Gustafsson L L, Warsame M
Abstract excerpt
We assessed the efficacy of sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) and DHFR/DHPS genotypes of Plasmodium falciparum in rural Tanzania, 3 years after their introduction as first- and second-line treatments for uncomplicated malaria, respectively. Under five children with uncomplicated malaria were given standard treatments of either SP (n=66) or AQ (n=30) and treatment outcomes after 14 and 28 days...
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