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Article

Influence of germline polymorphisms of GSTT1, GSTM1, and GSTP1 in familial versus sporadic breast cancer susceptibility and survival.

Familial cancer - 1 Jan 2008

Syamala Volga S, Sreeja Leelakumari, Syamala Vani, Raveendran Praveenkumar B, Balakrishnan Rajan, Kuttan Ratheesan, Ankathil Ravindran

Abstract excerpt

Identifying genes associated with familial inheritance of breast cancer continues to be a major goal of current research as the known high penetrance genes could be attributable for only a small percentage of the risk. So, it is hypothesized that the low penetrance genes may also modify the risk for familial breast cancer. In the present case-control study, undertaken to examine the influence of polymorphisms of...

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Source

Identifiers

PMID: 18080216
DOI: 10.1007/s10689-007-9177-1

Genes

GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Influence of germline polymorphisms of GSTT1, GSTM1, and GSTP1 in familial versus sporadic breast cancer susceptibility and survival.PMID 18080216Read ↗

Polymorphisms of glutathione S-transferase genes (GSTM1, GSTP1 and GSTT1) and breast cancer susceptibility.Semantic proximity Read ↗

Contribution of XPD (Lys751Gln) and XRCC1 (Arg399Gln) polymorphisms in familial and sporadic breast cancer predisposition and survival: an Indian report.Semantic proximity Read ↗

Polymorphisms of GSTM1 and GSTT1 genes in breast cancer susceptibility: a case-control study.Semantic proximity Read ↗

Lack of influence of glutathione S-transferase gene deletions in sporadic breast cancer in Pakistan.Semantic proximity Read ↗

Genetic polymorphisms in GSTM1, GSTP1, and GSTT1 and the risk for breast cancer: results from the Shanghai Breast Cancer Study and meta-analysis.Semantic proximity Read ↗

Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) variants and breast cancer risk in Burkina Faso.Semantic proximity Read ↗

Familial versus sporadic breast cancer.Semantic proximity Read ↗

GSTP1 methylation and polymorphism increase the risk of breast cancer and the effects of diet and lifestyle in breast cancer patientsSemantic proximity Read ↗

Pooled analysis indicates that the GSTT1 deletion, GSTM1 deletion, and GSTP1 Ile105Val polymorphisms do not modify breast cancer risk in BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Glutathione-S-transferase M1, T1 and P1 polymorphisms, and breast cancer risk, in BRCA1/2 mutation carriers.Semantic proximity Read ↗

Genetic polymorphism at the glutathione S-transferase (GST) P1 locus is a breast cancer risk modifier.Semantic proximity Read ↗

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