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Article

Protein therapeutics for junctional epidermolysis bullosa: incorporation of recombinant beta3 chain into laminin 332 in beta3-/- keratinocytes in vitro.

The Journal of investigative dermatology - 1 Jun 2008

Igoucheva Olga, Kelly Aislinn, Uitto Jouni, Alexeev Vitali

Abstract excerpt

Junctional epidermolysis bullosa (JEB) is an inherited mechanobullous disease characterized by reduced adherence of the epidermal keratinocytes to the underlying dermis, and is often caused by the absence of functional laminin 332 due to the lack or dysfunction of its beta3 chain. As there are no...

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Share to Cell Adhesion
Share to Endoplasmic Reticulum
Share to Epidermolysis Bullosa, Junctional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Integrin beta3

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Source

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Identifiers

PMID: 18079746
DOI: 10.1038/sj.jid.5701197
PMCID: PMC3357058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18079746-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Protein therapeutics for junctional epidermolysis bullosa: incorporation of recombinant beta3 chain into laminin 332 in beta3-/- keratinocytes in vitro.PMID 18079746Read ↗

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