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Article

A universal algorithm for de novo decrypting of heterozygous indel sequences: a tool for personalized medicine.

Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2008

Lam Ching-Wan

Abstract excerpt

INTRODUCTION: Indels (insertions/deletions) are important DNA sequence variations because of the high frequency in the human genome, the deleterious effects on the reading frame and protein expression, and the association with disease and disease susceptibility of common diseases. In a recent study with a human individual with the whole genome sequenced, 292,102 heterozygous indels and 559,473 homozygous indels...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18078814
DOI: 10.1016/j.cca.2007.11.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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