Article
Pancreatitis risk in primary hyperparathyroidism: relation to mutations in the SPINK1 trypsin inhibitor (N34S) and the cystic fibrosis gene.
The American journal of gastroenterology - 1 Feb 2008
Felderbauer Peter, Karakas Elias, Fendrich Volker, Bulut Kerem, Horn Tilman, Lebert Rainer, Holland-Letz Tim, Schmitz Frank, Bartsch Detlef, Schmidt Wolfgang E
Abstract excerpt
OBJECTIVE: Primary hyperparathyroidism (pHPT)-related hypercalcemia is considered to represent a risk factor for the development of pancreatitis. We therefore explored whether mutations in genes that were previously identified to increase the risk for pancreatitis coexist in a cohort of 826 patients with pHPT prospectively studied between 1987 and 2002. METHODS: Among 826 patients with pHPT, 38 patients were...
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