Article
Universal false discovery rate estimation methodology for genome-wide association studies.
Human heredity - 1 Jan 2008
Forner Karl, Lamarine Marc, Guedj Mickaël, Dauvillier Jérôme, Wojcik Jérôme
Abstract excerpt
Genome-wide case-control association studies aim at identifying significant differential markers between sick and healthy populations. With the development of large-scale technologies allowing the genotyping of thousands of single nucleotide polymorphisms (SNPs) comes the multiple testing problem and the practical issue of selecting the most probable set of associated markers. Several False Discovery Rate (FDR)...
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