Article
[Transmission disequilibrium test for nonsyndromic cleft lip and palate and segment homeobox gene-1 gene].
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology - 1 Sept 2007
Wu Ping-An, Li Yun-Liang, Wu Han-Jiang, Wang Kai, Fan Guo-Zheng
Abstract excerpt
OBJECTIVE: To investigate the relationship between muscle segment homeobox gene-1 (MSX1) and the genetic susceptibility of nonsyndromic cleft lip and palate (NSCLP) in Hunan Hans. METHODS: One microsatellite DNA marker CA repeat in MSX1 intron region was used as genetic marker. The genotypes of 387 members in 129 NSCLP nuclear family trios were analyzed by polymerase chain reaction (PCR) and denaturing...
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