Article
[Genetic variation of MSX1 has a sexual dimorphism in non syndromic cleft palate in the Chilean population].
Revista medica de Chile - 1 Jul 1998
Blanco R, Jara L, Villaseca C, Palomino H, Carreño H
Abstract excerpt
BACKGROUND: Recent studies in mice have demonstrated that the Msx-1 homebox gene is implicated in cleft palate. Thus, it has been suggested that its human homologue, MSX1 (HOX-7), located in chromosome 4 could be involved in the etiology of non syndromic cleft lip palate. AIM: To study the linkage between non syndromic cleft palate and variations of MSX1 gene. PATIENTS AND METHODS: Seventy three patients with non...
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