Article
[Genetic variation of MSX1 has a sexual dimorphism in non syndromic cleft palate in the Chilean population].
Revista medica de Chile - 1 Jul 1998
Blanco R, Jara L, Villaseca C, Palomino H, Carreño H
Abstract excerpt
BACKGROUND: Recent studies in mice have demonstrated that the Msx-1 homebox gene is implicated in cleft palate. Thus, it has been suggested that its human homologue, MSX1 (HOX-7), located in chromosome 4 could be involved in the etiology of non syndromic cleft lip palate. AIM: To study the linkag...
Topics
- Alleles
- Chile
- Cleft Lip
- Cleft Palate
- Female
- Gene Frequency
- Genetic Heterogeneity
- Genetic Variation
- Homeodomain Proteins
- Humans
- MSX1 Transcription Factor
- Male
- Sex Characteristics
- Transcription Factors
