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Article

Methylation of the TPEF‐ and PAX6‐promoters is increased in early bladder cancer and in normal mucosa adjacent to pTa tumours

7 Dec 2007

Abstract excerpt

OBJECTIVE: To evaluate CpG island methylation patterns of cancer-associated genes for their applicability as molecular biomarkers for the detection of superficial bladder cancer and for the discrimination of invasive from noninvasive tumours. PATIENTS AND METHODS: We analysed the methylation status of CpG islands in the promoter region of the cancer-associated genes GSTP1, DAPK, MDR1, TPEF, PAX6, and TSLC1 in...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 18070176
DOI: 10.1111/j.1464-410x.2007.07322.x

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