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Article

Mutation analysis of the parkin and PINK1 genes in American Caucasian early-onset Parkinson disease families.

Neuroscience letters - 3 Jan 2008

Deng Hao, Le Weidong, Shahed Joohi, Xie Wenjie, Jankovic Joseph

Abstract excerpt

Mutations in the parkin gene and the PTEN-induced putative kinase 1 gene (PINK1) have been identified as the most common causes of autosomal recessive early-onset Parkinson disease (EOPD). To investigate the presence of the parkin and PINK1 gene mutation(s) and to explore genotype-phenotype correlations in American Caucasian families with EOPD from North American, we screened these two genes in probands of six...

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Source

Identifiers

PMID: 18068301
DOI: 10.1016/j.neulet.2007.10.018

Genes

PINK1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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