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Article

Mutations in cardiac myosin heavy chain genes cause familial hypertrophic cardiomyopathy.

Molecular biology & medicine - 1 Apr 1991

Seidman C E, Seidman J G

Abstract excerpt

Familial Hypertrophic Cardiomyopathy (FHC) is a genetically inherited disorder of heart muscle. Over the past 40 years many studies have been done to describe in detail the clinical presentation of this disease and its associated pathophysiological consequences. The primary focus of this review is to discuss more recent studies involving the genetic mapping of one locus on chromosome 14, which causes FHC, and...

Topics

Amino Acid Sequence
Cardiomyopathy, Hypertrophic
Chromosomes, Human, Pair 14
Genetic Linkage
Humans
Molecular Sequence Data
Mutation
Myocardium
Myosins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1806760

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1806760-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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