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Article

The genetic basis of hypertrophic cardiomyopathy.

Journal of molecular and cellular cardiology - 1 Dec 1992

Elstein E, Liew C C, Sole M J

Abstract excerpt

In this article we review the techniques of molecular biology as they apply to the elucidation of the genetic basis of hypertrophic cardiomyopathy. We review the evidence for linkage to chromosome 14 and the specific mutations described to date. The evidence for genetic heterogeneity is presented. We speculate on the pathophysiology of the disease from the perspective of the known molecular defects and review the...

Topics

Cardiomyopathy, Hypertrophic
Genetic Linkage
Humans
Mutation
Myosins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1293318
DOI: 10.1016/0022-2828(92)91087-l

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1293318-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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