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CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges

16 Aug 2012

Abstract excerpt

The cancer stem cell (CSC) hypothesis, despite the limitations of the currently available models and assays, has ushered in a new era of excitement in cancer research. The development of novel strategies for anti-tumour therapy relies on the use of biomarkers to identify, enrich, and/or isolate the cell population(s) of interest. In this context, various cell characteristics and antigen expression profiles are...

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PMID: 22899341
DOI: 10.1002/path.4086

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