Article
LMNA Cardiomyopathy: Important Considerations for the Heart Failure Clinician.
Journal of cardiac failure - 1 Dec 2023
Rosario Karen Flores, Karra Ravi, Amos Kaitlyn, Landstrom Andrew P, Lakdawala Neal K, Brezitski Kyla, Kim Han, Devore Adam D
Abstract excerpt
BACKGROUND: A diagnosis of Lamin proteins A and C cardiomyopathy (LMNA-CM) not only impacts disease prognosis, but also leads to specific guideline-recommended treatment options for these patients. This etiology is fundamentally different from other genetic causes of dilated CM. METHODS AND RESULTS: LMNA-CM often presents early in the third to fourth decades and there is an age-dependent penetrance of nearly 90%...
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