Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glioblastoma multiforme: the role of DSB repair between genotype and phenotype.

Oncogene - 10 Dec 2007

Fischer U, Meese E

Abstract excerpt

Glioblastoma is the most frequent primary brain tumor in adults. The average survival time of less than 1 year did not improve notably over the last three decades. The dismal prognosis of glioblastoma patients is largely due to the striking radioresistance of this tumor. Here, we attempt a combined view on the genetics, the repair mechanisms and the radioresistance of glioblastoma. Specifically, we address the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to DNA Breaks, Double-Stranded
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to Genotype

Share to Glioblastoma

Share to Phenotype

Source

Identifiers

PMID: 18066094
DOI: 10.1038/sj.onc.1210878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glioblastoma multiforme: the role of DSB repair between genotype and phenotype.PMID 18066094Read ↗

DNA repair mechanisms and their clinical impact in glioblastomaSemantic proximity Read ↗

DNA damage repair in glioblastoma: current perspectives on its role in tumour progression, treatment resistance and PIKKing potential therapeutic targetsSemantic proximity Read ↗

Chemotherapeutic Drugs: DNA Damage and Repair in GlioblastomaSemantic proximity Read ↗

Extrachromosomal DNA: Redefining the pathogenesis of glioblastomaSemantic proximity Read ↗

Mechanisms of Resistance to Current Glioblastoma TherapiesSemantic proximity Read ↗

DNA Repair and Resistance of Gliomas to Chemotherapy and RadiotherapySemantic proximity Read ↗

DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology.Semantic proximity Read ↗

EGFRvIII and DNA Double-Strand Break Repair: A Molecular Mechanism for Radioresistance in GlioblastomaSemantic proximity Read ↗

The Role of Mismatch Repair in Glioblastoma Multiforme Treatment Response and ResistanceSemantic proximity Read ↗

DNA repair genes in astrocytoma tumorigenesis, progression and therapy resistanceSemantic proximity Read ↗

Targeting the DNA Damage Response to Overcome Cancer Drug Resistance in GlioblastomaSemantic proximity Read ↗

Incidence, clinicopathologic, and genetic characteristics of mismatch repair gene-mutated glioblastomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.