Article
Mutation-prone points in thrombin receptor.
Journal of thrombosis and thrombolysis - 1 Apr 2008
Wiwanitkit Viroj
Abstract excerpt
BACKGROUND: Thrombin receptor (TR) is a G-protein-coupled receptor that transmits cellular responses to coagulant proteases in a variety of cell types in the vasculature and other tissues. Mutation within TR can be seen. Presently, the prediction of protein nanostructure and function is a great challenge in the proteomics and structural genomics era. METHODS: To identify the points vulnerable to mutation is a new...
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