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Article

Fibrinogen Magdeburg I: a novel variant of human fibrinogen with an amino acid exchange in the fibrinopeptide A (Aalpha 9, Leu-->Pro).

Thrombosis research - 25 Jan 2003

Meyer Michael, Kutscher Gerlinde, Stürzebecher Jörg, Riesener Gabriele, Lutze Gerd

Abstract excerpt

INTRODUCTION: The exchange of Aalpha 16, Arg for Cys or His is the most common molecular defect in dysfibrinogenemia directly affecting the thrombin cleavage site involved in fibrinopeptide A (FPA) release. Other amino acid exchanges within the fibrinopeptide A have been only rarely reported. MATERIALS AND METHODS: In clinically asymptomatic dysfibrinogenemic patients with low functional plasma fibrinogen (Fg)...

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Identifiers

PMID: 12706644
DOI: 10.1016/s0049-3848(03)00114-2

Genes

FGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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