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Article

Trypsinogen copy number mutations in patients with idiopathic chronic pancreatitis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Jan 2008

Masson Emmanuelle, Le Maréchal Cédric, Chandak Giriraj R, Lamoril Jérôme, Bezieau Stephane, Mahurkar Swapna, Bhaskar Seema, Reddy D Nageshwar, Chen Jian-Min, Férec Claude

Abstract excerpt

BACKGROUND & AIMS: We have recently reported that the triplication of a approximately 605 kilobase segment containing the PRSS1 (encoding cationic trypsinogen) and PRSS2 (encoding anionic trypsinogen) genes causes hereditary pancreatitis. Here we went further to investigate whether this copy numb...

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Source

Identifiers

PMID: 18063422
DOI: 10.1016/j.cgh.2007.10.004

Genes

PRSS1
PRSS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18063422-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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