Article
The hnRNP and cytoskeletal protein raver1 contributes to synaptic plasticity.
Experimental cell research - 10 Mar 2008
Lahmann Ines, Fabienke Manuela, Henneberg Berenike, Pabst Oliver, Vauti Franz, Minge Daniel, Illenberger Susanne, Jockusch Brigitte M, Korte Martin, Arnold Hans-Henning
Abstract excerpt
Raver1 is an hnRNP protein that interacts with the ubiquitous splicing regulator PTB and binds to cytoskeletal components like alpha-actinin and vinculin/metavinculin. Cell culture experiments suggested that raver1 functions as corepressor in PTB-regulated splicing reactions and may thereby increase proteome complexity. To determine the role of raver1 in vivo, we inactivated the gene by targeted disruption in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.