Article
Amt2 permease is required to induce ammonium-responsive invasive growth and mating in Cryptococcus neoformans.
Eukaryotic cell - 1 Feb 2008
Rutherford Julian C, Lin Xiaorong, Nielsen Kirsten, Heitman Joseph
Abstract excerpt
The conserved AmtB/Mep/Rh family of proteins mediate the transport of ammonium across cellular membranes in a wide range of organisms. Certain fungal members of this group are required to initiate filamentous growth. We have investigated the functions of two members of the AmtB/Mep/Rh family from the pathogenic basidiomycete Cryptococcus neoformans. Amt1 and Amt2 are low- and high-affinity ammonium permeases,...
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