Article
Identification of apolipoprotein E Guangzhou (arginine 150 proline), a new variant associated with lipoprotein glomerulopathy.
American journal of nephrology - 1 Jan 2008
Luo Boxun, Huang Fengxian, Liu Qicai, Li Xiaoyan, Chen Wenfang, Zhou Shu-Feng, Yu Xueqing
Abstract excerpt
BACKGROUND/AIMS: Lipoprotein glomerulopathy (LPG) is a rare disease characterized by thrombus-like substances in markedly dilated glomerular capillaries and elevated plasma levels of apolipoprotein E (apoE). Previous studies have shown that genetic disorders of apoE may contribute to the pathogenesis of LPG, but LPG may not be caused by apoE gene mutations in Chinese patients. This study investigated the...
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