Article
Predicting RNA secondary structure by the comparative approach: how to select the homologous sequences.
BMC bioinformatics - 28 Nov 2007
Engelen Stéfan, Tahi Fariza
Abstract excerpt
BACKGROUND: The secondary structure of an RNA must be known before the relationship between its structure and function can be determined. One way to predict the secondary structure of an RNA is to identify covarying residues that maintain the pairings (Watson-Crick, Wobble and non-canonical pairings). This "comparative approach" consists of identifying mutations from homologous sequence alignments. The sequences...
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