Article
Liver and colon DNA oxidative damage and gene expression profiles of rats fed Arabidopsis thaliana mutant seeds containing contrasted flavonoids.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Apr 2008
Luceri Cristina, Giovannelli Lisa, Pitozzi Vanessa, Toti Simona, Castagnini Cinzia, Routaboul Jean-Marc, Lepiniec Loic, Larrosa Mar, Dolara Piero
Abstract excerpt
Plant polyphenols, such as flavonoids, comprise many compounds, ranging from simple phenolic molecules (i.e. flavonols, anthocyanins) to polymeric structures with high molecular weight (as proanthocyanidins, PAs). We investigated the effects of flavonoids by feeding Wistar rats Arabidopsis thaliana seeds carrying mutations in key enzymes of the flavonoid biosynthetic pathway (15% w/w seeds for 4 weeks). The seeds...
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