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Article

The angiotensin‐converting enzyme insertion/deletion and the endothelin ‐134 3A/4A gene polymorphisms in patients with chronic plaque psoriasis

18 Sept 2007

Abstract excerpt

BACKGROUND: Psoriasis is a common chronic inflammatory skin disease. Vasoactive peptides such as endothelin-1 (ET-1) and bradykinin have previously been implicated in the pathogenesis of chronic plaque psoriasis. The angiotensin-converting enzyme (ACE) gene carries a 287-base pair insertion/deletion (I/D) gene polymorphism, which is associated with plasma concentrations of bradykinin-degrading ACE. A functional...

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Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
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Identifiers

PMID: 18031458
DOI: 10.1111/j.1600-0625.2007.00620.x

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