Article
Association between the insertion/deletion polymorphism of the angiotensin I-converting enzyme gene and risk for psoriasis in a Chinese population in Taiwan.
The British journal of dermatology - 1 Apr 2007
Chang Y-C, Wu W-M, Chen C-H, Lee S-H, Hong H-S, Hsu L-A
Abstract excerpt
BACKGROUND: Genetic factors play an important role in susceptibility for psoriasis. The angiotensin I-converting enzyme (ACE) is expressed by keratinocytes. Administration of ACE inhibitors may induce or exacerbate psoriasis in clinical practice. Thus, ACE gene variants may contribute to the genetic background of psoriasis. OBJECTIVES: To assess the role of the ACE insertion/deletion (I/D) polymorphism in...
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