Article
Perinatal infection by human immunodeficiency virus type 1 (HIV-1): relationship between proviral copy number in vivo, viral properties in vitro, and clinical outcome.
Journal of medical virology - 1 Dec 1991
De Rossi A, Pasti M, Mammano F, Ometto L, Giaquinto C, Chieco-Bianchi L
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) isolates from 25 perinatally HIV-1 infected children were classified according to their capacity to replicate in vitro as rapid (R), intermediate (S/R) and slow (S) variants. R-type viruses replicated on peripheral blood mononuclear cells (PBMCs) and gr...
Topics
- Child
- Child, Preschool
- Clone Cells
- Female
- Genetic Variation
- HIV Infections
- HIV-1
- Humans
- Infant
- Leukocytes, Mononuclear
- Maternal-Fetal Exchange
- Organ Specificity
- Polymerase Chain Reaction
- Pregnancy
- Pregnancy Complications, Infectious
- Prognosis
- Proviruses
- Transcriptional Activation