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Article

Combined Use of Genome-Wide Association Data and Correlation Networks Unravels Key Regulators of Primary Metabolism in Arabidopsis thaliana.

PLoS genetics - 1 Oct 2016

Wu Si, Alseekh Saleh, Cuadros-Inostroza Álvaro, Fusari Corina M, Mutwil Marek, Kooke Rik, Keurentjes Joost B, Fernie Alisdair R, Willmitzer Lothar, Brotman Yariv

Abstract excerpt

Plant primary metabolism is a highly coordinated, central, and complex network of biochemical processes regulated at both the genetic and post-translational levels. The genetic basis of this network can be explored by analyzing the metabolic composition of genetically diverse genotypes in a given plant species. Here, we report an integrative strategy combining quantitative genetic mapping and...

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PMID: 27760136
DOI: 10.1371/journal.pgen.1006363
PMCID: PMC5070769

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