Article
Germline clone analysis for maternally acting Drosophila hedgehog components.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Selva Erica M, Stronach Beth E
Abstract excerpt
Many of the genes of Drosophila melanogaster have their transcripts deposited in developing oocytes. These maternally loaded gene products enable an otherwise homo-zygous mutant embryo to survive beyond the first stage of development for which the gene product is required. Zygotic mutations that disrupt the Hedgehog signal transduction pathway typically yield a segment polarity 'lawn of denticles' cuticle...
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