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Article

Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells.

Atherosclerosis - 1 Apr 2004

Tan P H, Chan C, Xue S A, Dong R, Ananthesayanan B, Manunta M, Kerouedan C, Cheshire N J W, Wolfe J H, Haskard D O, Taylor K M, George A J T

Abstract excerpt

The vascular endothelial cell (EC) plays an essential role in the pathogenesis of inflammation, transplant rejection and tumour metastasis. Most research on vascular ECs uses human umbilical vein endothelial cells (HUVECs). However, HUVECs are derived from immune-naive foetal tissue, and show sig...

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PMID: 15064090
DOI: 10.1016/j.atherosclerosis.2003.12.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15064090-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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