Article
Lactoferrin Glu561Asp polymorphism is associated with susceptibility to herpes simplex keratitis.
Experimental eye research - 1 Jan 2008
Keijser S, Jager M J, Dogterom-Ballering H C M, Schoonderwoerd D T, de Keizer R J W, Krose C J M, Houwing-Duistermaat J J, van der Plas M J A, van Dissel J T, Nibbering P H
Abstract excerpt
Lactoferrin plays an important role in the defense against infections, including herpes simplex virus (HSV) keratitis. We studied the impact of three single nucleotide polymorphisms in the human lactoferrin gene on the susceptibility to HSV infections of the eye and the severity of such infections. Lactoferrin gene polymorphisms were determined by PCR combined with restriction fragment length analysis in 105 HSV...
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