Article
SARS-CoV accessory protein 7a directly interacts with human LFA-1.
Biological chemistry - 1 Dec 2007
Hänel Karen, Willbold Dieter
Abstract excerpt
The SARS-CoV accessory protein 7a is a type I membrane protein with an extracellular domain of 81 amino acid residues. It is described to be expressed during infection and to be a component of the virus particle surface. In this study, we demonstrate that protein 7a binds directly and specifically to human lymphocyte function-associated antigen 1 (LFA-1) on the cell surface of Jurkat cells. The binding is...
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