Article
Genomic signatures individualize therapeutic decisions in non-small-cell lung cancer.
Expert review of molecular diagnostics - 1 Nov 2007
Anguiano Ariel, Potti Anil
Abstract excerpt
Gene expression signatures have been developed in an effort to dissect the biologic phenotypes of malignancies. These signatures have tremendous power to identify new cancer subtypes and to predict clinical outcomes based on patterns of gene expression. Expression profiles specific to a phenotype can be derived from in vitro data, as well as from patient cohorts with clinically relevant outcomes. In addition to...
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