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Article

Combining radiomic phenotypes of non-small cell lung cancer with liquid biopsy data may improve prediction of response to EGFR inhibitors.

Scientific reports - 11 May 2021

Yousefi Bardia, LaRiviere Michael J, Cohen Eric A, Buckingham Thomas H, Yee Stephanie S, Black Taylor A, Chien Austin L, Noël Peter, Hwang Wei-Ting, Katz Sharyn I, Aggarwal Charu, Thompson Jeffrey C, Carpenter Erica L, Kontos Despina

Abstract excerpt

Among non-small cell lung cancer (NSCLC) patients with therapeutically targetable tumor mutations in epidermal growth factor receptor (EGFR), not all patients respond to targeted therapy. Combining circulating-tumor DNA (ctDNA), clinical variables, and radiomic phenotypes may improve prediction of EGFR-targeted therapy outcomes for NSCLC. This single-center retrospective study included 40 EGFR-mutant advanced...

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Share to Carcinoma, Non-Small-Cell Lung
Share to Circulating Tumor DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, erbB-1

Share to Image Processing, Computer-Assisted

Share to Liquid Biopsy

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Share to Tomography, X-Ray Computed

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Identifiers

PMID: 33976268
DOI: 10.1038/s41598-021-88239-y
PMCID: PMC8113313

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