Article
Association of tumor necrosis factor-alpha-238G>A and apolipoprotein E2 polymorphisms with intracranial hemorrhage after brain arteriovenous malformation treatment.
Neurosurgery - 1 Oct 2007
Achrol Achal S, Kim Helen, Pawlikowska Ludmila, Trudy Poon K Y, McCulloch Charles E, Ko Nerissa U, Johnston S Claiborne, McDermott Michael W, Zaroff Jonathan G, Lawton Michael T, Kwok Pui-Yan, Young William L
Abstract excerpt
OBJECTIVE: We previously reported specific genotypes of polymorphisms in two genes, tumor necrosis factor-alpha (TNF-alpha-238G > A) and Apolipoprotein E (ApoE e2), as independent predictors of new intracranial hemorrhage (ICH) in the natural course of untreated brain arteriovenous malformations. We hypothesized that the risk of posttreatment ICH would also be greater in patients with brain arteriovenous...
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