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Article

Apolipoprotein E modifies neurological outcome by affecting cerebral edema but not hematoma size after intracerebral hemorrhage in humans.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jan 2000

James Michael L, Blessing Robert, Bennett Ellen, Laskowitz Daniel T

Abstract excerpt

INTRODUCTION: To address the mechanisms by which apoE polymorphism affects functional outcome after intracerebral hemorrhage in humans, we tested the hypothesis that the presence of the APOE4 allele results in amplified inflammatory responses and increased cerebral edema. METHODS: We prospectively enrolled and collected data on 21 adult patients consecutively admitted to Duke University Hospital with...

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Identifiers

PMID: 19251191
DOI: 10.1016/j.jstrokecerebrovasdis.2008.09.012
PMCID: PMC2699750

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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