Article
Correlates of ACE activity in macroalbuminuric type 2 diabetic patients treated with chronic ACE inhibition.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Apr 2008
Nikzamir Abdolrahim, Nakhjavani Manouchehr, Esteghamati Alireza, Rashidi Armin
Abstract excerpt
The activity of the renin-angiotensin-aldosterone system (RAAS) plays an important role in the development and progression of diabetic nephropathy. However, the effect of angiotensin-converting enzyme (ACE) inhibition on the RAAS appears to be modulated by a number of factors including the I/D polymorphism of the ACE genotype. In this study, we attempted to find independent correlates of ACE activity in 121...
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