Article
Polymorphisms of angiotensin converting enzyme and plasminogen activator inhibitor-1 genes in diabetes and macroangiopathy1.
Kidney international - 1 Nov 1998
Kimura H, Gejyo F, Suzuki Y, Suzuki S, Miyazaki R, Arakawa M
Abstract excerpt
BACKGROUND: An insertion or deletion (I/D) polymorphism in the angiotensin converting enzyme (ACE) gene and a 4/5-guanine tract polymorphism (4G/5G) in the promoter region of the plasminogen activator inhibitor-1 (PAI-1) gene are associated with the plasma activities of these substances and with...
Topics
- Adult
- Aged
- Base Sequence
- Diabetes Mellitus, Type 2
- Diabetic Angiopathies
- Diabetic Nephropathies
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Peptidyl-Dipeptidase A
- Plasminogen Activator Inhibitor 1
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Single-Stranded Conformational
